ARICEPT 5, 10 and 23 mg

Ask the doctor about another dosing option for your loved one.

ARICEPT 23 mg is for moderate to severe Alzheimer's disease.

Family get-togethers, high school and college graduations, valuable lessons shared long ago – the people in your life have given you some great things. While you're realistic about the nature of Alzheimer's, as their caregiver, you want to do what you can. If your loved one with moderate to severe Alzheimer's is taking ARICEPT (donepezil HCl) 10 mg, ask the doctor if ARICEPT 23 mg may help.

About ARICEPT 5, 10 and 23 mg.

ARICEPT comes in 5 mg, 10 mg and 23 mg doses.
ARICEPT 5 mg and 10 mg are indicated for mild to moderate Alzheimer's. ARICEPT 10 mg and 23 mg are indicated for moderate to severe Alzheimer's. ARICEPT 5 mg is the starting dose. It can be increased to 10 mg after 4–6 weeks. If your loved one with moderate to severe Alzheimer's has been on ARICEPT 10 mg for at least 3 months, it may be time to ask the doctor about ARICEPT 23 mg.

ARICEPT is not for everyone. Your loved one should not take ARICEPT if they are allergic to any ingredients in ARICEPT or to medicines that contain piperidines. Ask your loved one's doctor if you are not sure.

ARICEPT 23 mg vs. ARICEPT 10 mg.

ARICEPT 23 mg was compared to ARICEPT 10 mg in a large clinical study of patients with moderate to severe Alzheimer's disease. ARICEPT 23 mg showed improvement over ARICEPT 10 mg on mental function, though it did not show improvement on overall patient functioning. In the study, more people who took ARICEPT 23 mg experienced increased side effects.

In this study, more people who took ARICEPT 23 mg experienced increased side effects. Many more people taking ARICEPT 23 mg experienced nausea and vomiting than those taking ARICEPT 10 mg. These side effects may get better after the patient takes ARICEPT for a while. Other side effects that were seen more often with ARICEPT 23 mg were stomach ulcers, gastrointestinal bleeding, and weight loss. People of lower weight (less than 121 lbs) may have increased nausea, vomiting, and weight loss when taking ARICEPT 23 mg.

With Alzheimer's disease, it's important to remember that while ARICEPT treats the symptoms of Alzheimer's disease, it is not a cure. All patients will get worse over time, even if they take ARICEPT 23 mg.

Ask the doctor about giving your loved one ARICEPT 23 mg, a prescription medication for moderate to severe Alzheimer's disease.

INDICATION

ARICEPT® (donepezil HCl) is a prescription medicine to treat mild, moderate, and severe Alzheimer's disease.

DOSING INFORMATION

Before starting on ARICEPT 23 mg/day, patients should be on ARICEPT 10 mg/day for at least 3 months. The starting dose of ARICEPT is 5 mg/day and can be increased to 10 mg/day after 4–6 weeks. Please take ARICEPT as prescribed by the doctor.

IMPORTANT SAFETY INFORMATION

  • ARICEPT is not for everyone, including people who are allergic to any ingredients in ARICEPT or to medicines that contain piperidines.

  • Tell the doctor if your loved one takes nonprescription or prescription medicines, including those used to treat Alzheimer's or Parkinson's disease; anticholinergic medicines, such as allergy or cold medicine; medicines to treat bladder or bowel spasms; or certain asthma medicines.

  • ARICEPT may cause slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient faints while taking ARICEPT. People may also have seizures while taking ARICEPT. They may also have difficulty passing urine. Lung problems, including asthma, may worsen with the use of ARICEPT. Tell the doctor that the patient takes ARICEPT before they have any procedure that may require anesthesia, including dental and medical procedures or surgery.

  • People at risk for stomach ulcers or who take certain other medicines, such as aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs), should tell their doctor because serious stomach problems, such as bleeding, may get worse.

  • In a study, more side effects were seen with ARICEPT 23 mg than with ARICEPT 10 mg. Many more people taking ARICEPT 23 mg experienced nausea and vomiting than those taking ARICEPT 10 mg. These side effects may get better after the patient takes ARICEPT for a while. Other side effects that were seen more often with ARICEPT 23 mg were stomach ulcers, gastrointestinal bleeding, and weight loss. People of lower weight (less than 121 lbs) may have increased nausea, vomiting, and weight loss when taking ARICEPT 23 mg.

  • Other side effects of ARICEPT may include diarrhea, difficulty sleeping, vomiting, or muscle cramps. Some people may feel tired or may have loss of appetite.